The short duration was due to the difficulty in accommodating participants for 24 hours per. Would your patients with type 2 diabetes benefit from this macrobiotic diet? 24 (16; 43) 12.3 (9.9; 23). Browse journals by subject. Accept. This website uses cookies to ensure you get the best experience on our website. Ma- Pi 2 macrobiotic diet and type 2 diabetes mellitus: pooled analysis of short- term intervention studies - Porrata- Maury - 2. Diabetes/Metabolism Research and Reviews. Review Article. Authors. C. Porrata- Maury,Corresponding author. Finlay Institute, Havana, Cuba. 1-12 of 105 results for Books: "macrobiotic diet kushi" "macrobiotic diet kushi". Macrobiotic diet - Topic. Serving & Presentation Tips for a Macrobiotic Meal - Duration: 105 seconds. Those from 17 to 24 showed an increase from 39 to 44.4 percent. T h e standard macrobiotic diet has been practiced widely throughout history in every major culture. Correspondence to: Carmen Porrata- Maury, Finlay Institute, Havana, Cuba. E- mail: cporrata@infomed. Search for more papers by this author. 24 105 F4 ReviewM. Bin,Traditional Tibetan Medicine Hospital, Beijing, China. Search for more papers by this author. B. Baba- Abubakari,Tamale Teaching Hospital, Tamale, Ghana. Search for more papers by this author. M. Pianesi. International Association Un Punto Macrobiotico, Tolentino, Italy. Search for more papers by this author. Summary. The macrobiotic, Ma- Pi 2 diet (1. T2. DM). This pooled analysis aims to confirm results from four, 2. Ma- Pi 2 diet, carried out in Cuba, China, Ghana and Italy. Baseline and end of study biochemical, body composition and blood pressure data, were compared using multivariate statistical methods and assessment of the Cohen effect size (d). Results showed that all measured indicators demonstrated significant changes (p < 0. The global effect size of the diet was Italy (1. China (1. 7. 9), Cuba (1. Ghana (0. 9. 8). The magnitude of the individual effect on each variable by country, and the global effect by country, was independent of the sample size (p > 0. Similarly, glycemia and glycemic profiles in all four studies were independent of the sample size (p = 0. The Ma- Pi diet 2 significantly reduced glycemia, serum lipids, uremia and cardiovascular risk in adults with T2. DM. These results suggest that the Ma- Pi 2 diet could be a valid alternative treatment for patients with T2. DM and point to the need for further clinical studies. Mechanisms related to its benefits as a functional diet are discussed. Diabetes/Metabolism Research and Reviews published by John Wiley & Sons, Ltd. Introduction. Diet and type 2 diabetes mellitus. Poor metabolic control is a frequent finding in diabetes; in Italy, for example, two- thirds of institutionally- treated patients with type 1 diabetes and half of those with type 2 diabetes mellitus (T2. DM) do not show good metabolic control (according to plasma glucose, Hb. A1c, low- density lipoprotein (LDL) cholesterol and blood pressure), and 3. The conventional management of T2. DM and severe insulin resistance is recognized as being difficult and frustrating . Results from scientific studies currently suggest that an effective diet for diabetes must be rich in fibre, whole- grain cereals, vegetables and legumes and poor in simple carbohydrates, refined cereals, fats and foods of animal origin . This variability is thought to be related to several factors, including the type of carbohydrate or starch (amylose versus amylopectin), the food preparation methods (cooking procedures, heating); the fasting time, the pre- prandial glucose level, the distribution of macronutrients in the diet and the individual doses of insulin and resistance levels . Moreover, some studies suggest that the current standard definition of macronutrients fails to capture important information . This replacement technique has also been associated with a decrease in cardiovascular diseases . Taken together, overall results suggest that a good diet for T2. DM should not only take into account the GI and glycemic load, but also the supply of dietary fibre, micronutrients and phytochemical compounds with recognized biological activity (bioactive compounds), which could have important consequences on health status and on carbohydrate metabolism. Whole- grain fibre has been associated with an improvement in peripheral insulin sensitivity and also with increases in the pancreas . More significant physiological responses to whole- grain fibre intake include a decrease in serum cholesterol, modification of the glycemic response and improvement in bowel functioning. Almost all water- soluble whole- grain fibre fractions reduce serum cholesterol. Good sources of this dietary fibre are whole- grain cereals, legumes and green vegetables. A high intake of water- soluble fibre is able to reduce serum cholesterol and LDL cholesterol levels by 2. In particular, inulin (high in chicory and onions) has shown a remarkable hypolipemic effect in subjects affected by obesity and hyperlipemia. Evidence suggests that as little as 9 g of inulin per day for four weeks is enough to have a favourable effect on serum lipids . In addition, several phenolic compounds from whole- grain cereals have a strong antioxidant capacity in vivo. Many of these bioactive compounds are bound to grain cell walls and reach the colon unchanged, and are then released during the fermentation process . Whole- grain cereals are excellent sources of fat- soluble antioxidants, such as phytosterols (as gamma- oryzanol), tocopherols and tocotrienols (7. HMG- Co. A reductase, the key enzyme in cholesterol synthesis . Studies show that an evening meal rich in non- digestible carbohydrates can reduce post- prandial glucose after a high- GI breakfast; this response is thought to be caused by short- chain fatty acids (SCFAs: acetate, propionate and butyrate) produced by the fermentation of non- digestible carbohydrates by the colonic microbiota . Several hypotheses have been postulated as to how SCFAs mediate the glucose- lowering effect. SCFAs may delay gastric emptying . This research was also able to show that a reduced glucose response to a 5. This indicates that food- associated factors can acutely influence peripheral insulin sensitivity and suggests that butyrate, derived from colonic fermentation of non- digestible carbohydrates, could be involved in the overnight meal effect, and could prevent the late post- prandial rise in pro- inflammatory cytokines IL- 6 and TNF- . Moreover, this effect may be due to the anti- inflammatory properties of SCFAs . Considering the physiological significance of adiponectin and HDL cholesterol for T2. DM, these findings suggest that dietary millet may also have the potential to ameliorate this disease . Animal protein contains sulphur- containing amino acids (methionine, homocysteine and cysteine), whose oxidation generates sulphate, a non- metabolizable anion, which constitutes a major determinant of the daily acid load. This metabolic acidosis increases progressively with age as a result of the physiological decline in kidney function. Usually, the kidneys implement compensating mechanisms, aimed at restoring acid- based balance, such as the removal of anions, the conservation of citrate, the enhancement of kidney ammoniogenesis, and the urinary excretion of ammonium ions. These adaptive processes result in low serum bicarbonate, high serum anion gap, a low urine p. H, hypocitraturia and nitrogen and phosphate wasting. Research has shown that people consuming a diet based on animal protein have higher renal net acid excretion and a more acidic urinary p. H than people eating a plant- based diet . Urinary sulphate excretion is inversely correlated with urine p. H. Univariate analysis of a cross- sectional study on healthy subjects found that urinary sulphate was significantly higher in insulin- resistant subjects, compared with those with normal insulin sensitivity. These findings suggest a link between animal protein, endogenous acid production and insulin resistance . Even a very mild degree of metabolic acidosis, which induces skeletal muscle resistance to insulin action and dietary acid load, may be an important variable in predicting hypertension and cardiovascular risk in the general population and in diabetes and chronic kidney failure . Unlike animal products, vegetable proteins do not induce renal vasodilation or glomerular hyperfiltration . High animal protein intake and excessive body weight have been shown to result in similar hemodynamic adaptations in both type 1 and T2. DM where elevated renal plasma flow, glomerular filtration rate and kidney size have been noted early in the course of the disease, compared with non- diabetic individuals. Both the consumption of vegetable proteins and the careful metabolic control of diabetes help to ameliorate these modifications in kidney function through an improvement of the acidosis state . In healthy individuals, even a slight degree of metabolic acidosis results in a decreased sensitivity to insulin and subsequent impairment of glucose tolerance. The incidence of diabetes mellitus and glucose intolerance is much higher in persons with a lower urinary p. H than in normal volunteers . These relatively recent changes in dietary lifestyles have contributed to the dramatic modification of the human global health picture and have generated a permanent high level of acidification and inflammation in those consuming these Western diets . It was conceived by Mario Pianesi, conceiver, founder and president of the Un Punto Macrobiotico Association, in Italy, for the treatment of T2. DM . This diet has been shown to reduce plasma glucose, Hb. A1c, serum cholesterol, serum triglycerides, blood pressure and insulin consumption, and increase urine p. H, in short- term studies (2. T2. DM . These studies were carried out in Cuba in 2. In all studies, patients were selected from specialized endocrinology services according to the same inclusion and exclusion criteria. In all four studies, the same Ma- Pi 2 diet was administered to each patient. It consisted of 4. Ma- Pi 2 diet were used such as kale, broccoli, lettuce and chive); and 8–1. Bancha tea (caffeine- free green tea). Daily average energy intake was 2. The Ma- Pi 2 diet contained 1. It provided nutrients and phytocompounds with antioxidant, hypoglycemic and hypolipemic effects, such as vitamin C, . Individual foods varied, according to availability in each country. In Italy and Ghana, patients were kept in a hotel or in a hospital, respectively, for the duration of the study. Robot Check. Enter the characters you see below. Sorry, we just need to make sure you're not a robot. For best results, please make sure your browser is accepting cookies.
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