Find a comprehensive guide to possible side effects including common and rare side effects when taking Baclofen (Baclofen Tablets) for healthcare professionals and. Get emergency medical help if you have any of these signs of an allergic reaction to Xalatan: hives; difficulty breathing; swelling of your face. The beneficial effects of cranberry supplements have long been recognized by health and nutritional experts. Cranberry contains phenols which are a type of. Drowsiness and weakness are possible side effects of Gabapentin. You may seem more sleepy and fatigued than usual. GENERIC NAME: baclofen BRAND NAME: Gablofen, Lioresal DISCONTINUED BRAND: Kemstro. DRUG CLASS AND MECHANISM: Baclofen is an oral and injectable medication that. Baclofen - Side Effects, Dosage, Interactions. Baclofen is a prescription drug used to treat muscle spasms from multiple sclerosis and Huntington's disease as well as spinal cord injuries and spinal cord diseases. Medical experts do not recommend baclofen for muscle spasms caused by rheumatoid arthritis, cerebral palsy, Parkinson's disease, or stroke, because research to date does not support such use. Baclofen is an antispastic muscle relaxant. Researchers don't know exactly how baclofen works; however, in general, it blocks nerve signals from muscles at the level of the spinal cord and it may also depress the central nervous system. The Food and Drug Administration (FDA) approved baclofen in 1. Lioresal, which was made by Novartis. The FDA approved generic baclofen in the 1. Today, only generic versions of baclofen are available. A case report published in Therapeutic Advances in Psychopharmacology in 2. The research also showed that baclofen may help reduce withdrawal symptoms as well as the effects of marijuana. A separate study, published in the Journal of Neuroscience in 2. The drug works by interfering with the brain's early response to drug cues. Baclofen Pump. You can take baclofen as a pill or via an intrathecal baclofen (ITB) pump. Learn about drug side effects and interactions for the drug Baclofen (Baclofen Tablets). In ITB therapy, your doctor will insert a small catheter under the skin of your abdomen, near your waist. The pump stores and releases the prescribed amount of baclofen through the catheter, using a small motor, directly into your spinal fluid. ITB can be an option for people who experience side effects taking baclofen in pill form as it requires smaller doses of the drug and thus keeps side effects to a minimum. Your doctor will need to refill your ITB pump system every one to three months. The system battery typically lasts five years, at which time your doctor will need to replace the device. Baclofen Warnings. Once you start taking baclofen, don't stop taking it suddenly on your own. If you need to stop, your doctor will lower your dose gradually. Stopping baclofen suddenly can lead to a dangerous withdrawal reaction that can include hallucinations (seeing or hearing things that are not there) and seizures. Your kidneys eliminate baclofen from your system. Take baclofen with caution if you have kidney disease and reduced kidney function because the drug can build up in your system. Baclofen is not recommended to treat muscle spasms caused by a stroke. Baclofen can cause more side effects in people with a history of stroke. Baclofen can make you drowsy and affect your balance, so don't drive or operate heavy machinery until you know how baclofen affects you. Other conditions you should tell your doctor about before taking baclofen include: Kidney disease. Parkinson’s disease. Stroke. Seizures (epilepsy)Ulcers. Cerebral palsy. Mental health or mood disorders such as schizophrenia. Rheumatoid arthritis. The FDA has not approved baclofen for children younger than 1. Find information about common, infrequent and rare side effects of baclofen oral. Drug information provided by: Micromedex. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side. Baclofen and Pregnancy. Studies have linked baclofen to birth defects in animals. Because of this, it is considered unsafe to use during pregnancy. Before taking this drug, tell your doctor if you are pregnant or may become pregnant. Baclofen may pass into breast milk, so also tell your doctor if you are breastfeeding or plan to breastfeed. If you're a woman, ask your doctor about a possible risk for developing ovarian cysts while on baclofen. Make sure you doctor knows if you have a history of ovarian cysts. Baclofen “High” and Recreational Use. Numerous online and anecdotal reports have suggested that some people abuse baclofen for a narcotic- like . Baclofen overdose can lead to: Take baclofen only as directed by your doctor, and keep this and all other drugs away from children, teenagers, and anyone for whom the drug has not been prescribed.
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How to Trim an Artichoke. Squeeze half a lemon into a large bowl of water: If you are trimming more than one artichoke, squeeze half a lemon into a large bowl of ice water. You will be dropping trimmed artichokes into this bowl to keep them from browning while you work others. Snap off outer green petals, then pull off yellow petals: Start by snapping off the artichoke petals and tossing them into a large empty bowl. When you get to the yellow petals, just pull them off. Wipe the exposed surface with the other half of the lemon you cut. Pull out the pink tipped petals: Take care when you get to the pink center of the artichoke petals. There are sharp spines on the end of the inner leaves. Pull them out. 4 Use a paring knife to dig out the fuzzy choke. You will want to slice off the narrowest layer of the heart to get all of the choke without cutting away too much of the delicious heart. A note on this whole process. The majority of Afro-Brazilians live in the nine states of the country's northeastern section—home to nearly one-third of all Brazilians. Ephedra Warehouse's top 10 list of the best weight loss supplements available. All of these ephedra fat burners are the best on the market. Online shopping for diet pills and exercise equipment. Wholesale prices and everyday low prices on diet products, excellent quality on imported merchandise. Don’t do it if there are distractions. You will be using a sharp knife close to your hands. Since artichokes are tough when raw, you can easily cut yourself if you take your eye off what you are doing. Rub cut lemon over exposed artichoke heart: Once the fuzzy choke is out, smear the cut lemon all over the exposed heart. This prevents the heart from oxidizing and turning brown. An artichoke is still perfectly edible when oxidized, it just is not particularly attractive. Slice off all but the last inch or so of the stem. Rub lemon juice on the cut end. Trim the hard green exterior of the rest of the heart. Cut away from you as you rotate the artichoke, slicing off just the hard green part and leaving the light green underneath. Rub this with lemon. To finish, slice the outside layer off the stem and then coat the whole heart one more time with lemon. Drop into the lemon- water bath and go on to the next one. Here's a tip: as your cut lemon gets used up, put it in the water bath, which will help keep the bath’s citric acid content high, and help keep the artichokes from browning. Is there such a thing as The Happiness Diet? Doctor reveals A-Z of foods that trim your waistline AND make you feel good. Dr Sarah Brewer, medical. Discover the list of 26 Brazilian beauty secrets revealed for women worldwide below so you can be more attractive inside out. In the diet industry, don’t mistake marketing for evidence. This time around we took the time to write a detailed review of Sweet Sweat, examining the side effects. Top 1. 0 Ephedra Diet Pills. Ephedra Warehouse has put this Top 1. All the ephedra pills below are made with the finest ingredients and are all very effective. You can't go wrong with any of them. Black Spider is the golden child pre- workout stimulant of Cloma Pharma and is comparable to the Original ECA Stack. ECA stacks, a blend of ephedra, caffine, and white bark (aka aspirin), have proven time and again to be the most effective blend to achieve weight loss, boost energy, and suppress your appetite. Black spider combines the ECA stack with green tea, theobromine, cayenne, ginger root, and yohimbe in its unique proprietary blend to maximize effectiveness. Colma Pharma raises the stakes even higher by adding Vitamin B6 and Vitamin B1. Your Price: $4. 9. On Sale $2. 8. 9. Cocoa powder, the cheap antioxidant. Everybody should drink a cup of cocoa daily. Snacking doesn't automatically mean weight gain. These healthy snack ideas can help you lose weight by keeping you full and satisfied throughout the day. Weight Loss Systems offers a meal replacement diet plan that will help you lose 2-4 lbs a week. On the New Lifestyle Diet, you’ll lose weight fast with delicious low carb, high protein, liquid diet shakes, bars, and gluten free snacks. Cocoa is a nutritional powerhouse and a superfood. Its health benefits are very many and more are being discovered. One of such benefits is weight loss. Good quality cocoa requires only 2. ORAC units, so a kilogram should last 5. However, as you will also eat other healthy foods, do not plan to get all your ORAC’s from cocoa. See the ORAC score sheet. Cocoa is an antioxidant. Chocolate products have a higher total flavanol content on a per weight basis than many other plant- based foods and beverages, such as apples and red wine. Studies show that flavanols and other flavonoid components in chocolate are rapidly absorbed in humans in a dose- dependent manner. The potential health effects of flavanols in certain chocolates are seen in a variety of functions, including antioxidant properties, reductions in platelet activity (Rein et al, 2. The chemical structure of flavonoids reveals their antioxidant capacity (Steinberg et al, 2. These flavonoids can scavenge free radicals, and chelate (combine with) redox active metal ions. Such bioactive compounds could contribute to the maintenance of an integrated network of cellular and plasma oxidant defense mechanisms, to vascular wall tone, and to a reduction in platelet reactivity with a subsequent reduction in the risk for clot formation. The flavan- 3- ols are the major antioxidant components of different cocoa ingredients and chocolate preparations. How To Speed Up Weight Loss High Daily Intake Of Fruits, Vegetables, Greens and Beans Can Help You Take Control By Jackie Wicks PEERtrainer Founder. Weight Loss Worksheet Please complete steps 1-5 below and click submit. Oxygen radical absorbance capacity (ORAC) data show that chocolate, as a whole food, has a potent antioxidant capacity when compared with other phytochemical- rich foods such as garlic, blueberries, and strawberries. Chocolate products have higher ORAC values than most other flavanol- containing foods. Cocoa is a potentially rich dietary source of flavonoids. High concentrations of flavonoids are present in certain cocoas, predominately as the flavanol monomers (. Cocoa powder provides a higher concentration of polyphenols than milk or dark chocolate (Chocolate Manufacturers Asociation). The absorpion of polyphenols can depend factors such as what else you have been eating at the time. Blood plasma antioxidant capacity (measured by the total antioxidant potential (TRAP) assay) increased more than 2- fold within 3 hr and remained unchanged for 4 hr after the consumption of cocoa extract (Zhu et al, 2. Blood levels of the polyphenol epicatechin rise after the consumption of chocolate, reflecting rapid absorption. Important cocoa flavanols are epicatechin and catechin. Epicatechin and catechin have a relatively high water solubility. Get your grocery shopping list ready! When you're trying to shed a few pounds, the inventory in your pantry (and the weight loss tools and gadgets) will be the. Dietary flavanols, such as those found in cocoa, display variable oral absorption, with reported values varying from less then 1 to greater than 5. Baba et al., 2. 00. Rein et al., 2. 00. Hollman et al., 2. Some of this difference is due to investigations that assess absorption based on urinary vs plasma measures (Richelle et al., 1. Baba et al., 2. 00. In a study by Schramm (2. Other published data showed similar plasma levels (Richelle et al., 1. Wang et al., 2. 00. Schramm’s conclusion was that food can have a significant effect on polyphenolic absorption. The consumption of bread and sugar significantly increased flavanol absorption compared to when they consumed cocoa alone. Origin of Cocoa. Cacao is the unprocessed cocoa bean from the plant Theobroma cacao and originated deep in the equatorial rain forests of the Americas. Chocolate was first discovered by the Mayas when they used the cocoa bean from the Cacao tree as an ingredient in their favorite drink “xocotlatl. Over the centuries, the use of cacao has evolved to what we now know as chocolate (processed bean in solid or liquid form containing varying percentages of cocoa liquor, cocoa butter, sugar, and milk), and commercial cultivation has extended globally to include equatorial regions of Africa and Asia. The unprocessed cocoa bean has a seed coat, also termed bran, which accounts for 1. The bran is a good source of insoluble fiber (4. Cocoa powder contains less than 2% bran (Steinberg et al, 2. Cocoa butter makes up 5. The predominant fatty acids in cocoa butter are saturated (stearic; 1. Palmitic and stearic acid are chemically defined as saturated fatty acids (SFA). Cocoa flavonoids. Flavonoids are found in a variety of foods and beverages, including cranberries, peanuts, apples, chocolate, tea and red wine. Flavonoids are a sub- group of the broader class of polyphenols; there are more than 4,0. Flavanols are a more specific sub- class of flavonoids. Although numerous polyphenolic compounds are present in the cocoa bean, cocoa powder is particularly rich in a subclass of polyphenolics known as flavonoids. Cocoa liquor has three time more ORAC generating antioxidants than dark chocolate (Steinberg et al, 2. The primary flavonoids in cocoa and chocolate are the fiavan- 3- ols (monomers) catechin and epicatechin (monomeric units) and proanthocyanidins (also termed procyanidins), which are polymeric compounds comprising catechin and epicatechin subunits (Zhu et al 2. Procyanidin oligomers make up 1. Time, temperature and other manufacturing processes such as alkalization, can lower the flavonoid content in chocolate. With the proper processing and manufacturing controls in place, substantial amounts of these potentially beneficial compounds can be retained from the cocoa bean. With good production methods, cocoa powder can contain as much as 1. Dark chocolate is formulated with a higher percentage of cocoa bean liquor than is milk chocolate, so it often contains larger amounts of flavonoids. This is an important distinction because not all chocolates are equal sources of flavonoids. The nutrient density (fat content) of a given flavonoid- containing food should be considered when recommending appropriate sources of dietary phytochemicals. Flavonoid bioavailability in humans ranges from 1% to 2. Steinberg et al, 2. There is also a variability between differing compounds such as quercetin, epicatechin, and soy isoflavones. The flavonoid chemical structure largely determes the absorption, distribution, metabolism and excretion, and ultimately the biologic properties of these phenolic compounds. Flavonoids circulating in plasma, including those derived from cocoa, occur primarily as glucuronide, methyl and sulfate conjugates, or combinations thereof, formed through enzyme action in the small intestine and liver. Direct evidence of bioavailability is measured as plasma concentrations of the flavonoid or its metabolites. Indirect evidence can be obtained from biomarkers such as plasma antioxidant capacity, LDL oxidation susceptibility, platelet function, vascular tone, and immune responsiveness. Flavonoid- rich chocolate contains epicatechin (a monomeric flavanol) that is rapidly absorbed in humans. In healthy human adults, plasma epicatechin concentrations can approach 1 . The rise in plasma epicatechin concentrations is dose- dependent and dictated by the flavonoid concentration in the chocolate eaten. Plasma epicatechin concentrations return within six to eight hours to baseline values. Dimeric procyanidins are also found in human plasma after the consumption of flavonoid- rich cocoa. The monomers and oligomers can have markedly differently biological or physiological effects, so research is continuing. Health Benefits. Plant- derived polyphenols are historically a significant and natural constituent of the human diet. Diets rich in flavonoids (a class of polyphenols) have been associated with a reduced risk for cardiovascular disease (Zhu et al, 2. Generally, the consumption of cocoa powder (2. HDL) to LDL. A higher ratio of HDL to LDL is associated with a lower risk for heart disease. In a study where people consumed chocolate with bread and water on two separate occasions: first consuming 4. The total polyphenol intake from chocolate was 8. Blood samples were drawn before chocolate consumption and at intervals of one, two, three and four hours after consumption. Blood analysis found levels of the polyphenol epicatechin rose after consumption of each chocolate sample, reflecting rapid absorption. Another study showed that feeding 3. LDL cholesterol’s resistance to oxidation within two hours of cocoa consumption (CMA, 2. In another trial, the inhibitory effect of the cocoa extract was stronger than ascorbic acid. Examples include beta- carotene, vitamin C, and alpha- tocopherol. Dark chocolate has more than 1. ORAC units and milk chocolate has about 6,7. Chocolate Manufacturers Association. Unsweetened powdered cocoa starts out with almost twice as much antioxidants as dark chocolate, but when it's diluted with water or milk and sugar to make hot chocolate, the flavonoid total per serving plummets to about half that in milk chocolate. In different terms, a 4. A study of a tribe of indians (Kuna Indians living on islands off Panama, Central America ) who consume an average of five cups of cocoa a day has shown that chocolate may prevent high blood pressure. Researchers are investigating a link between consumption of flavanol- rich cocoa and nitric oxide synthesis. There is also a link between antioxidants in chocolate and a reduction in platelet aggregation in blood, and an increase in . Nitric oxide plays such an important role in the maintenance of healthy blood pressure and, in turn, cardiovascular health (Prof Norman Hollenberg of Brigham and Women's Hospital and Harvard Medical School, 2. Flavanols found in cocoa seem to play a role in helping the body use nitric oxide. Flavanols are one class of a group of naturally occurring substances called flavonoids, which are found in foods such as cocoa, dark chocolate, purple grape juice, and tea. Previous studies have also indicated that eating foods high in flavonoids can have positive effects on the heart. Two clinical studies conducted by Heiss et al (2. Germany, suggest that the flavanols found in cocoa and chocolate products may have positive effects on vascular health. Eating for Types O, A, B, & ABThe Promise. Could eating a diet based on your blood type - - O, A, B, or AB - - help you trim down and get healthier? That's the idea behind the Blood Type Diet, created by naturopath Peter J. D'Adamo. D'Adamo claims that the foods you eat react chemically with your blood type. If you follow a diet designed for your blood type, your body will digest food more efficiently. Could eating a diet based on your blood type-- O, A, B, or AB -- help you trim down and get healthier? That's the idea behind the Blood Type Diet. Reviews the Eat Right For YourType / Blood Type Diet, and questions the scientific evidence, benefits, nutritional credibility and health claims. You'll lose weight, have more energy, and help prevent disease. What You Can Eat. That depends on your blood type. Here's what D'Adamo recommends for each type: Type O blood: A high- protein diet heavy on lean meat, poultry, fish, and vegetables, and light on grains, beans, and dairy. D'Adamo also recommends various supplements to help with tummy troubles and other issues he says people with type O tend to have. Type A blood: A meat- free diet based on fruits and vegetables, beans and legumes, and whole grains - - ideally, organic and fresh, because D'Adamo says people with type A blood have a sensitive immune system. Type B blood: Avoid corn, wheat, buckwheat, lentils, tomatoes, peanuts, and sesame seeds. Chicken is also problematic, D'Adamo says. He encourages eating green vegetables, eggs, certain meats, and low- fat dairy. Type AB blood: Foods to focus on include tofu, seafood, dairy, and green vegetables. He says people with type AB blood tend to have low stomach acid. Avoid caffeine, alcohol, and smoked or cured meats. Blood Type O Diet Guidelines Type O—Oldest, most basic blood type, effective predators, survivors Type O’s unique traits. Blood Type O Foods to Avoid Exclude completely the AVOID foods from your diet. AVOID foods are POISON FOOD for your type. Your body creates antibodies to fight these. Level of Effort: High. If you don't already know your blood type, you'll need to find that out. The results will determine exactly what you need to do. Limitations: Depending on your blood type, you may need to severely restrict the foods you eat. Cooking and shopping: Your blood type will determine your shopping list and your choices when eating out. Packaged foods or meals? None required. In- person meetings? No. Exercise: The Blood Type Diet recommends exercises based on your blood type. For instance, it suggests yoga or tai chi for type A’s, and vigorous aerobic exercises like jogging or biking for up to an hour a day for type O’s. Does It Allow for Dietary Restrictions or Preferences? Because the diet dictates that you eat very specific types of food based on your blood type, it doesn't allow much for personal tastes. For example, if you're a big fan of meat and potatoes, you won't be very happy on the type A diet, which is mostly vegetarian. There are even recommendations about the types of spices and condiments you can use. If you're looking for a diet that's gluten- free, you should know that this diet doesn't ban gluten. You may be able to make choices that are gluten- free, if you read food labels carefully. What Else You Should Know. Cost: D'Adamo recommends a lot of specialty and organic foods (such as soy milk and carob chip cookies), which can be pricey. Vitamin and herbal supplements are also part of the diet. Support: You do this diet on your own. What Dr. Melinda Ratini Says: Does It Work? One study found that adults eating the type A diet showed improved health markers, but this occurred in everyone, not just those with type A blood type. In 2. 01. 3, a major review concluded that no evidence exists to support benefits of blood type diets. It's likely that you would lose weight, though, because the diet can be very restrictive. Is It Good for Certain Conditions? The Blood Type Diet makes recommendations based solely on your blood type. So, if you have a chronic condition (say, diabetes), you may be told to eat high protein, while another person with diabetes may have to avoid dairy or chicken. Diet for O Positive Blood Type. Blood group O is considered to be the oldest and the most common of all blood types. The following article provides information about. The Type O Profile Type O was an early success formula. It is the only blood type that carries two opposing blood type antibodies (one blood type A and another. The blood type diet recommends to Type O individuals fruits with an alkalizing effect that helps balance your body's pH level, making it less acidic. As someone with type O blood, you're an inherent meat eater, according to D'Adamo. You thrive best on animal protein from meat. O Negative Blood Type Diet. Here is an article explaining the O negative blood type diet. It is based on the book, 'Eat Right 4 Your Type' by Dr. This may conflict with your diabetes treatment plan. The American Diabetes Association recommends a more practical approach to your day- to- day eating. It also cautions against focusing on specific foods. In most cases it doesn't recommend cutting out any major food groups. The Blood Type Diet also fails to address other conditions such as heart disease, high blood pressure, or cholesterol. Any needed weight loss is sure to have a positive impact on these conditions. But no matter your blood type, you should follow the same guidelines issued by The American Heart Association (AHA) for a low- fat and low- salt diet. Also, everyone should aim for 1. The Final Word. On The Blood Type Diet, you’ll avoid processed food and simple carbs. That may be enough to help you lose some weight. But any weight loss on this diet has not been linked to your blood type. There’s also no research proving that this diet can aid in digestion or give you more energy. Although you'll buy and prepare your own foods on this plan, your choices are limited depending on your blood type. So be prepared to spend some time in the kitchen. The diet may quickly become expensive, too, since the author recommends you buy organics as well as his own line of supplements. If the Blood Type Diet intrigues you, consider this: The science is stacked behind traditional recommendations for healthy eating for weight loss - - not restrictions based on the type of your blood. Gastroparesis Symptoms, Treatment, Causes - What are gastroparesis symptoms and signs? What causes gastroparesis? Gastroparesis can be caused either by diseases of the stomach's muscles or the nerves that control the muscles, though often no specific cause is identified. The most common disease causing gastroparesis is diabetes mellitus, which damages the nerves controlling the stomach muscles. Gastroparesis also can result from damage to the vagus nerve, the nerve that controls the stomach's muscles, that occurs during surgery on the esophagus and stomach. Helicobacter pylori is a bacterial species that infects the stomach causing an increase in gastric acid and damaging the lining of the stomach.Scleroderma is an example of a disease in which gastroparesis is due to damage to the stomach's muscles. Occasionally, gastroparesis is caused by reflexes within the nervous system, for example, when the pancreas is inflamed (pancreatitis). In such cases, neither the nerves nor the muscles of the stomach are diseased, but messages are sent through nerves from the pancreas to the stomach which prevents the muscles from working normally. Other causes of gastroparesis include imbalances of minerals in the blood such as potassium, calcium or magnesium, medications (such as narcoticpain- relievers), and thyroid disease. Gastroparesis can occur as an isolated problem or it can be associated with weakness of the muscles of other parts of the intestine, including the small intestine, colon and esophagus. What are gastroparesis symptoms and signs? The primary symptoms of gastroparesis are nausea and vomiting. Other symptoms of gastroparesis include bloating with or without abdominal distension, early satiety (feeling full quickly when eating), and in severe cases, weight loss due to a reduced intake of food because of the symptoms. Abdominal pain also is present frequently though the cause of the pain is unclear. The vomiting of gastroparesis usually occurs after meals; however, with severe gastroparesis, vomiting may occur without eating due simply to the accumulation of secretions in the stomach. The characteristic vomiting happens several hours after a meal when the stomach is maximally distended by the presence of food and secretions stimulated by the meal. Since the grinding action of the stomach is absent, the vomited food often contains larger pieces of recognizable food. Peptic ulcer disease is a problem of the gastrointestinal tract characterized by mucosal damage secondary to pepsin and gastric acid secretion. The Biology of Pancreatic Cancer. Data suggest that pancreatic cancer results from the successive accumulation of gene mutations. 14 The cancer originates in the. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015. Pancreatic adenocarcinoma. An error occurred while setting your user cookie. Please set your. browser to accept cookies to continue. This cookie stores just a. ID; no other information is captured. Accepting the NEJM cookie is. Home » Current Health Articles » Stomach Bloating A few weeks back, Tom Venuto, author of Burn the Fat, Feed The Muscle, caught wind of my May 5th and 6th Boston G-Flux seminar. And although he couldn’t make it out.The 4 Cycle Solution Weeks 7 - 8 Maintenance Cycle The “Diet Break” Meal Plans By: Shaun Hadsall. ATI-REFLUX DIET Your healthcare provider has advised you to begin an anti-reflux diet. This type of diet is actually easy to follow, requiring you to cut out just a. Berardi talks G- Flux with Tom Venuto. A few weeks back, Tom Venuto, author of Burn the Fat, Feed The Muscle, caught wind of my May 5th and 6th Boston G- Flux seminar. And although he couldn’t make it out to the event, he had a few questions for me. Well, as usually is the case, a few questions lead to a few questions more. If G-Flux can help you do both, then. John Berardi G-Flux represents the relationship between the amount of energy you ingest through your diet and the amount of. Diet for Gastro-Oesophageal Reflux. By Ms Caroline Salisbury. Gastro-oesophageal reflux (GOR) occurs when the stomach contents including acid move back up into the. Modifying one’s diet and lifestyle remains the foundation for treating the symptoms of reflux. Your goal is to prevent the problem by keeping. And we eventually ended up with a full- out, no- holds barred Q& A article covering everything from exercise volume to energy needs, to the value of calorie restriction. In fact, when the smoke cleared, we ended up with the most comprehensive and in- depth G- Flux interview that’s been published to date. Tom Venuto: John, Thank you for the interview. I’ve been following your work for years with interest, but the first time I heard you talk about “energy flux” or “G- flux”, it really got my attention and I said to myself, “He is right on the money with that one!” It fell right in line with my experiences as a bodybuilder and with what I’ve been teaching to my clients. I have a program called Burn The Fat, Feed The Muscle, which suggests that it’s better to exercise more (burn) and eat more (feed) than to try to lose fat by eating less and exercising less. Are we talking about the same concept here essentially, and if so, what are some of the biggest benefits of this approach? John Berardi: Well, first of all, it’s an honor to speak with you and to do this interview! I’m a huge fan of your work too! Secondly, you’re right on track with the exercise more/eat more thing. In fact, that’s exactly what G- Flux is all about.(Of course, we’re assuming here that the additional exercise is done properly and the additional food comes from the right sources and at the right times of the day.)The amazing thing is that by increasing G- Flux, even in energy balance (where calories in theoretically equal calories out), people see increases in sympathetic nervous system activity and metabolic rate. And these increases lead to increased lean mass and decreased fat mass. Again, even in energy balance. Now, this can get confusing so here’s an example. Take an individual eating 2. That person wouldn’t likely lose or gain any weight. They’re in energy balance and that means they’d be weight stable. Yet if we use the principles of G- Flux to boost this person’s food intake to 3. They’d assume that the increased intake and expenditure would cancel each other out, right. But researchers have shown that in such a situation there are increases in metabolic rate, losses of fat, and increases in lean mass! The weight might not always change but body comp certainly does. And that’s the power of G- Flux! Eat more, exercise more, build a better body. Tom Venuto: We’re not talking about simply eating larger and larger amounts of food at the same activity level and expecting our metabolism to continue increasing to match that, are we? I remember some gurus in the body building world who recommended that bodybuilders should eat outrageously large amount of calories based on this premise. One in particular back in the early 1. That sounds like a prescription for fat gain to me. With your model of G- flux, aren’t you referring to eating more at a higher, but manageable level, while also exercising more at the same time? This way, for fat loss we can still have a deficit, and for muscle gain we can still have a small surplus, but in both cases it would be at a higher level of energy expenditure? John Berardi: You’re right, G- Flux is not about simply “eating more to boost metabolism”. Flux means flow and we’re talking about energy flow into and out of the body. So G- Flux covers both the intake and expenditure sides of the equation. In essence, G- Flux is about exercising more so that you can eat more and all the while improve metabolism, lean mass and body fat %. At this point, let’s get real practical. There are essentially 2 steps to increasing G- Flux: Step 1 – Increase calorie expenditure through specific exercise strategies that include a mix of strength training, interval exercise, and low intensity exercise/cardio. Step 2 – Increase calorie intake to: a) Match this energy expenditure if you want to maintain your weight yet improve your body compb) Fall just below energy expenditure if you want to lose weight while improving metabolism and lean massc) To exceed energy expenditure if you want to gain weight while improving body comp. G- Flux is pretty much that simple! Tom Venuto: For fat loss, we know we need a calorie deficit, but you can have a deficit at a high energy intake or a deficit at a low energy intake. For example, you could have a 7. Or you could have a 7. That’s a pretty big difference in activity and double the food intake. Will there be a difference in body composition results between these two regimens? And if so, how do you explain that two 7. John Berardi: The whole goal of increasing G- Flux is boost total metabolic rate and, if fat loss is required, to allow you to eat more while still being in a negative energy balance. Simply put, it allows you to diet at 3. And personally, I MUCH prefer this! You see, by allowing you to eat more while still being in a negative energy balance, the principles of G- Flux lead to the following benefits: 1) Increased total food intake when dieting, a powerful psychological benefit. Increased micronutrient and phytochemical intake, leading to better function and better health. Increased sympathetic nervous system activity, leading to a faster metabolism. Increased nutrient partitioning, leading to less fat and more muscle. Tom Venuto: G flux sounds to me like the antithesis of CRON or calorie restricted optimal nutrition, which some people practice believing it will extend lifespan. In your discussions of G- flux, does this subject of life extension through calorie restriction ever come up from your readers or audiences and what is your response or criticism? John Berardi: Oh yeah, I hear this ALL THE TIME. Some believe that calorie restriction is the only way to enhance lifespan in humans. And to them it seems that the opposite – high levels of G- Flux – will shorten lifespan. Sure, this at first sounds logical. Yet as my grad school buddies always said, just because it’s logical doesn’t make it physiological. Yes, many animal models have demonstrated that reducing calorie intake by 3. But before dropping your calorie intake by 3. First, there are a lot of questions left unanswered. Just a few, for example, are: Do all these animal studies translate to humans? Are there other ways to live longer vs. After all, typical rat chow or monkey chow isn’t exactly healthy. It’s not even real food. Rats, for example, are fed chow pellets – in essence, processed, fast food! So they’re not eating all that healthy in the first place. What if they were actually fed a healthy higher calorie diet vs. What if they ate the equivalent of 5- 1. What if they exercised regularly? What if they supplemented with fish oil? What if they maintained low body fat? If you’re going to keep up your typical North American, low quality, high sugar, processed diet while refusing to exercise, then yes, calorie restriction might help you live longer. But that’s a choice that no one has to make. In the end, eating well, supplementing intelligently, and subscribing to a life- long exercise program may prove to be more powerful than calorie restriction. And you won’t have to suffer the psychological perils (restriction, deprivation) or physical perils (below) associated with this approach. That’s right; there are some health problems associated with calorie restriction. Mike Linksvayer, the example of a calorie restriction proponent detailed in a recent New York Times article, stands 6ft tall and 1. Mike is severly underweight. Now, that might be better than being overweight. Yet this low body weight presents its own risks as he ages. Studies show that those with low body weight and low muscle mass are at a higher risk for a loss of independence into their elder years. This is due to the natural losses in bone and muscle that occur with age. So Mike may be healthier than his friends now, but watch out Mike as you age! And here’s another interesting piece of data. No calorie restriction required. So, in the end, don’t stop eating just yet. Although calorie restriction works in animals, it’s not yet proven in humans. And if it does turn out to work, who cares? Calorie restriction is so difficult and carries its own risks including exchanging quality of life for longevity. Why not learn the good lifestyle habits associated with smart eating, proper supplementation, and lifelong exercise? That way you can eat, exercise, and be merry while living long and living well. Tom Venuto: If somebody decides to just eat less and not exercise, which is the case for many popular diet programs, what is the impact on performance, metabolism and body composition short term and also long term? John Berardi: Well, for starters, choosing not to exercise is a huge mistake for anyone, regardless of their goals. The human body was built for exercise and, over time, has developed with exercise as a survival necessity. Yet nowadays exercise has become unnecessary for survival and, on the whole, our society has become sedentary. This has lead to huge health and body composition problems. Plain and simple, it’s a fool’s choice not to exercise. Yet let’s say someone simply won’t exercise. In that case, eating less (while still eating well) is certainly better than eating whatever they feel like, whenever they feel like it – which will usually lead to overfeeding and under nourishing. However, assuming the no exercise, low calorie scenario, problems can still develop. For starters, muscle and bone mass will likely be lost. This means long- term problems like osteoporosis and sarcopenia. In other words, get ready for the nursing home. Also, metabolic power diminishes. Eating less while not exercising is like rapidly downshifting the metabolism. And this means that when the “diet” ends, it’s quite easy to gain fat. Lose weight - Live Well. With an account you can keep track of pages on the site and save them to this tab, which you can access on every page when you are logged in. Already have an account? We know, you would never order drugs illegally over the internet, or have your friend bring them back from vacation. But just in case you somehow ended up with the. 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HOW TO BEAT HEART DISEASE: Why it isn't fat that clogs up your arteries. What causes heart disease? A simple enough question, and one you might have thought was settled years ago. But the answer has become a subject of much debate — with implications for many of us on how we lead our lives and the medication we take. For years the finger of blame has pointed at cholesterol, a fatty substance produced by the liver. Scroll down for video While some cholesterol is vital (it helps produce hormones and vitamin D, for instance), the consensus has been that too much — or rather, too much of the bad form, known as low density lipoproteins (LDL) — damages the blood vessels. This leads to risk of blood clots, heart attacks and stroke. This thinking was confirmed in 2. Interheart study reported in the Lancet, which showed that 4. The message on cholesterol has been twofold: avoid foods rich in cholesterol- raising saturated fat such as butter, cream, milk and cheese, and if you’re at risk of heart disease, take cholesterol- busting statins. But is it time this two- track approach was rethought? CUTTING FAT CAN BE BAD FOR YOUCutting cholesterol has been a success, according to Professor Peter Weissberg, medical director of the British Heart Foundation, who says better diet — plus a four- fold drop in tobacco use — helped to halve death rates from heart disease between 1. The findings were controversial, but Dr Chowdhury is one of an increasing number of scientists who believe current heart health advice is misguided, if not harmful. Yes, according to the cholesterol charity Heart UK, which claims 4 tsp to 6 tsp of one of the spreads or a mini- drink a day can lower bad cholesterol by up to 1. That’s because they contain plant sterols that mimic human cholesterol and so, it’s claimed, effectively block its absorption into the bloodstream. Some experts, though, suggest Heart UK makes too much of the benefits of sterol- enriched foods. Even a 1. 0 per cent reduction won’t make that much difference to your health status, says Peter Weissberg, former Professor of Cardiovascular Medicine at the University of Cambridge and medical director of the British Heart Foundation. It says that if everyone at risk took a statin, 8,0. By last year, up to ten million Britons were taking the drugs. Of these, one and a half million had survived a heart attack; two million had severe chest pain (angina); with the remainder at risk because of high blood pressure, high cholesterol, obesity, smoking or diabetes. One difficult piece of research to explain, published in the American Heart journal in 2. Furthermore, your cholesterol falls naturally with age, particularly in older people with chronic health problems. 9783161495632 3161495632 Galatians and the Imperial Cult - a Critical Analysis of the First-century Social Context of Paul's Letter, Justin K. Kendall Jenner Diet, Workout and Health Secrets. So, what makes Kendall Jenner's looks so amazing? Check out her eating (diet), exercise (workout) habits. And it may be unhealthy to have low levels. A 2. 0- year study published in the Lancet in 2. They are misguided.’So, if cholesterol’s role is over- played, what does cause heart disease? One emerging theory is sugar, which is thought to promote inflammation inside the arteries. A study in the Journal of the American Medical Association found adults who have three sugary drinks a day had triple the chance of a heart attack. One theory is that sugar encourages a particular type of . If it’s too high, it puts strain on the heart and blood vessels over time. High blood pressure is a major cause of heart disease and the leading risk factor for strokes. But as there are no symptoms, it can remain untreated. While seven million adults in England have been diagnosed with high blood pressure, a further five million are unaware they, too, are affected, according to a recent report. Under current guidelines, people with low to normal blood pressure should have it checked only every five years. However, if you are overweight, over 6. African or Caribbean descent, you should be checked more often, even if your pressure appears to be normal. A recent Public Health England report warns high blood pressure is not being picked up soon enough, and suggests everyone should have their blood pressure tested at any opportunity. Regular monitoring or self- monitoring could also help to identify those who suffer from dramatically fluctuating high blood pressure. Work by Professor Peter Rothwell, of the Oxford Stroke Prevention Research Unit, found that people who had significant swings in blood pressure had a 1. Such people would benefit most from calcium channel blockers, which stabilise blood pressure (drugs such as ACE inhibitors and beta blockers reduce it). The healthiest is . It’s the smallest, most dense forms that are most dangerous because they can penetrate artery walls, setting off inflammation. If the clot closes the artery, that causes a heart attack.’ British experts acknowledge that the theory that inflammation is caused by sugar needs investigation. But increasingly researchers are suggesting it’s part of a bigger picture, with reducing arterial inflammation as the overall priority. Intriguingly, some evidence suggests statins may make an unexpected contribution here, reducing inflammation as well as performing their familiar duty of cutting cholesterol. In the words of Dr Malhotra: . HAVE A WEEKLY SAUNARegular saunas could cut the risk of heart disease by as much as 6. Finnish study. Middle- aged men who took frequent saunas were half as likely to die from heart conditions as those who didn’t take them. The heat raises heart rate, which effectively . BREAKFAST ON PORRIDGEOats contain a soluble fibre, beta- glucan, which lowers bad cholesterol. It forms a thick gel like wallpaper paste, which binds to cholesterol in the gut and prevents its absorption into the bloodstream. Just 3g of beta- glucan a day (an average- sized bowl of porridge or muesli provides 1. Dr Sarah Schenker. She suggests snacking on oatcakes (1g of beta- glucan each) or switching to oat bread (such as Hovis Hearty loaf, 0. Nuts have a beneficial effect on cholesterol levels, too, possibly because they contain plant sterols, which block the absorption of cholesterol. Try to eat a handful (2. MAKE SURE YOU FLOSS REGULARLYGum disease has been linked to hardening of the arteries and heart attacks — the bacteria that cause tooth decay are thought to trigger inflammation, which has been linked to heart disease. Experts recommend brushing regularly and flossing religiously (and that’s not just when there’s food stuck between your teeth — flossing also breaks down the biofilm that traps the gluey mass of bacteria). HAVE SEX TWICE A WEEKMen who have sex at least twice a week are 4. American Journal of Cardiology study. WEAR A SLEEP MASKLack of sleep is linked to a greater risk of heart attack death: fewer than six hours a night raises it by half, says a study by Warwick University. Visit GLAMOUR to see pictures of celebrity teeth makeovers, including Tom Cruise teeth and celebrities with bad teeth: We take a look at the stars who have put their. Lack of sleep interferes with the appetite hormones ghrelin and leptin, leading to obesity. Ensure that your bedroom is dark or wear a sleep mask, as light suppresses production of the sleep hormone melatonin. They found that attempts to lower salt levels were driving people to increase their consumption of starches and sugars. Dr James Di. Nicolantonio, a cardio- vascular research scientist at St Luke’s Mid America Heart Institute, who led the study, says: . BOOK A SUNNY HOLIDAYGoing on holiday regularly cuts the risk of dying from heart disease by a third, say researchers at the University of Pittsburgh. And a holiday somewhere sunny could boost the benefits. Last year, the universities of Southampton and Edinburgh found that sunshine alters levels of nitric oxide, which relaxes blood vessels, helping blood pressure to fall. EAT A POT OF YOGHURTA daily dose of . WATCH A FUNNY FILM WITH FRIENDSA good belly laugh can boost blood flow by more than 2. Research by Robert Provine, a U. S. DON'T DELAY GOING TO THE LOO A small study of people with early heart disease in Taiwan suggested that an over- full bladder can cause your heart to beat faster and put unnecessary stress on coronary arteries, triggering them to contract. GET A SIT- STAND DESKResearch suggests sitting for eight hours a day raises the risk of cardiovascular disease, cancer and diabetes by 4. One study found sitting for more than four hours means you’re twice as likely to get heart disease, even if you work out. Try a . Aim for a total of two hours at least, ideally four, a day. VARIDESK, from . DOWNLOAD A 'MINDFULNESS' APPA recent study by Brown University in the U. S. Though mindfulness — a form of meditation — is known to be deeply relaxing, the study’s lead author, epidemiologist Professor Eric Loucks, says mindful people also usually lead healthier lives. Cardiologist Dr Aseem Malhotra recommends Headspace, an app that teaches mindfulness techniques. Head space, free for ten days, then . CUT BACK ON SALAMIVegetarians have a lower risk of heart disease — but if you can’t stomach going fully veggie, a recent Harvard study found that switching from three meat- based meals a day to three a week cuts heart disease risk by 1. Replace meat with foods rich in vegetable oils, nuts and seeds, and fruit, vegetables and pulses to boost your fibre intake. An extra 2. 0g of fibre could lower bad cholesterol levels by 1. Pay particular attention to processed red meat such as sausages, salami, bacon and ham. A Swedish study last year found that men who ate the most processed red meat were more than twice as likely to die from heart failure. LOSE HALF A STONEStudies have consistently shown that losing 5 to 1. GLUG A LITTLE OLIVE OIL EVERY DAYThe Mediterranean diet — which is rich in fish, vegetables, fruit and olive oil — can protect against heart disease. But it’s olive oil in particular that appears to have a potent anti- inflammatory effect. Cardiologist Dr Aseem Malhotra, who says he has at least 4tbsp of extra virgin olive oil a day, explains: . Each is highly effective — provided it’s used for the right patients. Experts warn that patients need to understand exactly what each promises. The first option is a percutaneous coronary intervention (PCI) — often called angioplasties. There are 200 calories in a 1 bar serving of Slim-Fast Meal Bars - Chocolate Fudge Brownie. High Protein Meal on the Go Bar - Chocolate Chip Granola. Find helpful customer reviews and review ratings for SlimFast Meal Replacement Bars, Chocolate Fudge Brownie. Slim Fast Advanced Nutrition Meal Bar. Slim-Fast 3-2-1 Plan Meal Bars Chocolate Fudge Brownie - 5 ct: 9.17 OZ BOX . Slim-Fast 3-2-1 Plan Snack Bars Peanut Butter. Slim Fast Chocolate Fudge Brownie Meal Bar, 5 ct. Disclaimer: While we aim to provide accurate product information. See our disclaimer below. This Slim- Fast Chocolate Fudge Brownie Meal Bar, 5- count, is a smart meal replacement or snack. It contains a delicious combination of a rich, fudge brownie center smothered with a decadent chocolate coating that can satisfy any sweet tooth. Each protein meal bar has 8 grams of protein, 2. It works as a tasty alternative to a meal when you are on the Slim- Fast 3- 2- 1 plan. This pack contains 5 Slim- Fast meal bars. Slim- Fast Chocolate Fudge Brownie Meal Bar, 5- Count: Each Slim- Fast meal bar serving size is 5. Slim-Fast Diet is ranked: #20. If you’re replacing a Slim-Fast meal bar or. Chocolate cookie dough, fudge. Buy Kroger Slimfast Chocolate Fudge Brownie Protein Meal Bar online in Houston. Meal bar is 2. 00 calories(3. Rich, fudge brownie center smothered with a decadent chocolate coating. Slim Fast meal bar has 8g of protein. Slim- Fast meal bars. Protein meal bar works as a tasty alternative to a heavy meal when you are on the Slim- Fast 3- 2- 1 plan. See all diet foods and drinks. This Slim- Fast Chocolate Fudge Brownie Meal Bar, 5- count, is a smart meal replacement or snack. It contains a delicious combination of a rich, fudge brownie center smothered with a decadent chocolate coating that can satisfy any sweet tooth. Each protein meal bar has 8 grams of protein, 2. It works as a tasty alternative to a meal when you are on the Slim- Fast 3- 2- 1 plan. This pack contains 5 Slim- Fast meal bars. Chocolate Fudge Brownies With CocoaCalories in Slim- Fast Meal Bars. Please note that some foods may not be suitable for some people and you are urged to seek the advice of a physician before beginning any weight loss effort or diet regimen. Best Homemade Fudge BrowniesWhy Low- Carb Diets May Be Ideal for Most People. By Dr. Mercola. Jeff Volek, Ph. This article provides detailed information on the eight most popular diets today, including the Atkins Diet, the South Beach Diet, The Zone Diet, and more. It is interesting to see these different classification of facial shape, and my current area of research that shows just how intimately the shape of our faces are.
D., and registered dietitian and professor in the Human Science Department at Ohio State University, has done enormous work in the field of high- fat, low- carbohydrate diets, investigating how it affects human health and athletic performance. Stephen Phinney, a physician and true pioneer in this field, who has studied low- carb diets even longer than Volek. Starting out as a dietician, Volek was taught that low- fat diets were healthy and that saturated fats and cholesterol should be avoided. But in working with diabetics, he kept feeling that something was . I was at the time into very low- fat diets, thinking that was how I would optimize my own health. But I decided to experiment with a very low- carb diet. This fueled his passion for understanding how humans respond to diets that are very low in carbohydrates, and led him to continue his education. We're still sorting out a lot of the details, but clearly we need to change the way we feed Americans and the way we think about nutrition in order to reverse .. The Westernized diet constantly biases you toward using more nonfiber carbs for fuel. Healthy fat, meanwhile, is a far preferable sort of fuel, as it burns far more efficiently than carbs. As noted by Volek, humans evolved to primarily burn fat as fuel — not carbs — and yet that's not how we're feeding our bodies. Without generating ATP you cannot survive at all. The question is how to do that efficiently, without generating harmful reactive oxygen species (ROS), which can destroy your mitochondria and contribute to disease? Regardless of the fuel your body burns, you're going to generate carbon dioxide and water. But when you burn fat, you generate 3. That contributes to the metabolic problems we're seeing in this country. According to Volek, that's true for everyone, whether you're an elite athlete or a sedentary diabetic. In essence, the reason why low- carb diets work so well is because it helps you escape this non- fiber, carb- based metabolism that depends on insulin levels to drive blood sugar into cells and use carbs for fuel. Volek also introduces another term: . So when we're talking about dietary fats, we're referring to natural, unprocessed fat, found in real foods such as seeds, nuts, butter, olives, avocado, or coconut oil. Fats are critical for a number of health reasons. They contribute to the formation of cellular membranes, for example, and it's really difficult to have good biological function with impaired cell membranes. So, dietary fat serves two purposes: it serves as fuel; but it's also a foundational structural component of your biology. So if you're overweight, you want to teach your body to burn excess fat, and then, once you've reached your maintenance weight, the majority of fat your body will be burning is that from dietary sources. But how do you make this conversion — to allow your body to become adapted to burn fat as your primary fuel — starting with any excess body fat you already have? How to Make the Conversion from Burning Sugar to Burning Fat. In short, the key is to restrict non- fiber carbohydrates. It's important to make the distinction about which carbs we're talking about here, as vegetables are . As long as you're eating carbs, your body will try to burn those first. They're like the bully cutting in line. You may just think of them as kind of a throw- away nutrient too, because your body cannot store high levels of carb. You have to try to oxidize them and burn them first. But if you're carb intolerant, which is highly prevalent in this country, you can't burn carbs, by definition, very well. Your body then only has one alternative, and that's to convert the carbs you eat into fat. That happens to a greater extent to folks who are insulin resistant or carb intolerant. That really sets the stage for a lot of metabolic problems. Again coming back to how do you train the body to burn more fat; it all starts with removing the availability of carbohydrate because, as long as it's there, it's going to take precedence, and will simultaneously inhibit burning of fat. These are very sensitive and exquisite mechanisms in place for this to work. You eat just a single meal of carbs and your fat- burning shuts down right away. This is why a low- nonfiber carb diet works so well to shift fuel use over to fat. You restrict the amount of glucose and starches that you're consuming, and your body naturally shifts over to preferring fat for fuel. It does take some time to adapt to that. Your cells have to shift over their machinery to handle the increased levels of fat and lipid- based fuels. It takes a matter of weeks to get that adaptation. But once it's there, they're fairly robust adaptations that don't just go away. This is why there is an adaptation period to a low- carb diet. It can be disrupted though if you reintroduce carbs. But a lot of the adaptations do remain. However, we all vary how we respond to the same food, so this is not an exact recommendation. Some people can be in a full fat- burning state with full ketosis at a level of non- fiber carbs that's higher than 5. Others, especially if you're insulin resistant or have type 2 diabetes, may require less than 4. If you look at the nutrition facts on a processed food package, it will list total carbs, and that's not what we're talking about. Don't get confused about this or you'll get really nervous. You do need carbs, but you need most all of them from vegetables. You could have an 8. This will give you an objective measure of whether or not you're truly in ketosis, rather than just counting the grams of carbohydrates you consume. The appropriate level of carb for an individual is bit of a moving target, but it is a very important element to personalizing a diet, which I think is fundamental to this idea of personalized nutrition. It's finding the appropriate level of carb for you at any given point in your lifespan that allows you to maintain health. But there are people who are naturally very insulin sensitive and carb tolerant that don't need to be in ketosis to thrive. So there's certainly room for flexibility, depending on your individual situation. Ketogenic Diet Can Benefit Many Chronic Health Problems. Beyond insulin resistance and type 2 diabetes, there are a number of applications for a well- formulated ketogenic diet, including epileptic seizures, especially in kids who are unresponsive to drugs, and neurological conditions such as Alzheimer's and Parkinson's. Cancer is another area where ketogenic diets show great promise. There are multiple potential mechanisms by which a ketogenic diet would benefit, including epigenetic effects. We now know that the principal ketone body, beta hydroxybutyrate, is more than a metabolite. It's more than just an alternative fuel for the brain. It acts like a hormone or a potent signaling molecule that affects gene expression, including upregulating genes that are protective against oxidative stress and enhance the antioxidant status. Our knowledge and perspective on ketosis is expanding almost daily. It's all pointing toward positive health effects, which is quite interesting considering that for the last three or four decades, we've been demonizing ketones because we only associate it with ketoacidosis. Mental clarity is another great boon. According to Volek, the U. S. Being an efficient fat burner may also predispose you to a longer life. Ron Rosedale told me many years ago that the single most important variable for controlling the aging process is the ratio of fat versus carbohydrate you burn. The more fat you burn, the slower you're going to age in general. More recent research supports this notion. How Ketogenic Diet May Promote Longevity and Increased Muscle Mass. Recent research has found about a dozen genes associated with longevity. The primary function of one of these genes is to cripple the degradation of branched- chain amino acids, such as leucine, which can be useful for building muscle mass. Interestingly, in one of his books, Volek mentions that ketones share a close structural similarity to these branched- chain amino acids, and seem to be preferentially metabolized. In other words, ketones spare those branched- chain amino acids, leaving higher levels of them around, which promotes longevity and increased muscle mass. One of the reasons why we can survive so long without food is we enter into ketosis, and ketosis spares protein breakdown. One of a more consistent effect we see in people on a ketogenic diet is that leucine levels go up in the blood, because they're not being oxidized to the same level. Ketones are sparing oxidation and breakdown of important structural proteins, and therefore their levels or concentrations in the blood increase and allow them to do other important signaling- type functions. I do see a very positive interaction here with nutritional ketosis and protein metabolism in general in sparing of the branched- chain amino acids in particular, which are unique in that they are a preferential fuel, unlike other amino acids, which don't really serve as a fuel substrate. You don't want more protein than your body actually needs. As noted by Volek, this is an important point because there's a common misconception that low non- fiber carb diets are high- protein diets. In reality, a ketogenic diet must actually be moderate in protein because excessive protein is anti- ketogenic. On the other hand, you don't want to consume too little protein, as this may push you into a negative nitrogen balance. As a general rule, I recommend eating one- half gram of protein per pound of lean body mass per day, which for most sedentary folks is 4. The best approach is to measure ketosis to know you are not over- consuming protein. Most animal sources of protein maintain these essential amino acids . |
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